department of molecular biosciences, evanston, il 60208


Affiliations & Resources

Departments and Research Centers

Academic Programs

Pre-doctoral Training Programs


  • Biological NMR Center: The Structural Biology NMR facility comprises a four-channel 600 MHz Varian Inova instrument equipped with a cryogenic probe. Every structure displayed in the gallery has been solved based on data acquired using this instrument. The facility is staffed by a full-time manager.
  • UIC Center for Structural Biology: A super high-field resource comprising state-of-the-art 800 and 900 MHz spectrometers for structural biologists in the Chicago area.
  • Keck Biophysics Facility: The Keck facility hosts a wide array of spectroscopic, imaging, and analytical instruments for biophysical studies of macromolecules and macromolecular interactions. Over two dozen instruments are currently available and the facility is open to investigators from within as well as outside Northwestern. Virtually every project in the lab takes advantage of this valuable resource.
  • Analytical Services Laboratory: The ASL hosts a wide array of analytical instruments for chemistry and biochemistry research. We use the facility mostly for mass spectrometric analysis (ESI-MS and MALDI).
  • Advanced Photon Source: Northwestern structural biologists have access to the brightest source in the world for crystallographic analysis. Located in Argonne, the facility is an hour's drive from the Evanston campus.




  • MONSTER: A webserver for analyzing macromolecular complexes developed in our laboratory
  • BLAST: A suite of tools for identifying homologous sequences
  • CLUSTAL W: A tool for aligning multiple sequences
  • ScanProsite: A tool for detecting PROSITE patterns
  • ProfileScan: A tool for detecting remote homologues
  • Pfam: A tool for detecting remote homologues
  • ExPaSy: Proteomics server of the Swiss Institute of Bioinformatics
  • PHYLIP: Phylogenetic analysis suite
  • GENSCAN: A gene prediction tool
  • PredictProtein: Burkhard Rost's PHD suite for secondary structure prediction and other programs
  • JPred: A yet another tool for secondary structure prediction


  • RASMOL: Molecular graphics software for Macs, PCs, and Unix boxes (tutorial)
  • Swiss-PDBViewer: Molecular graphics software for protein structure analysis and modeling (tutorial)
  • RIBBONS: Molecular graphics software for making pretty images (manual)
  • MOLSCRIPT: Molecular graphics software for making pretty images (manual)
  • RASTER3D: Molecular graphics software for making pretty images - used in conjunction with MOLSCRIPT (manual)
  • GRASP: Molecular graphics software for making pretty images (primer)



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